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Towards precision medicine-based therapies for glioblastoma: interrogating human disease genomics and mouse phenotypes

BACKGROUND: Glioblastoma (GBM) is the most common and aggressive brain tumors. It has poor prognosis even with optimal radio- and chemo-therapies. Since GBM is highly heterogeneous, drugs that target on specific molecular profiles of individual tumors may achieve maximized efficacy. Currently, the C...

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Detalles Bibliográficos
Autores principales: Chen, Yang, Gao, Zhen, Wang, Bingcheng, Xu, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001238/
https://www.ncbi.nlm.nih.gov/pubmed/27557118
http://dx.doi.org/10.1186/s12864-016-2908-7