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Protection of CpG islands from DNA methylation is DNA-encoded and evolutionarily conserved

DNA methylation is a repressive epigenetic modification that covers vertebrate genomes. Regions known as CpG islands (CGIs), which are refractory to DNA methylation, are often associated with gene promoters and play central roles in gene regulation. Yet how CGIs in their normal genomic context evade...

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Detalles Bibliográficos
Autores principales:	Long, Hannah K., King, Hamish W., Patient, Roger K., Odom, Duncan T., Klose, Robert J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001583/ https://www.ncbi.nlm.nih.gov/pubmed/27084945 http://dx.doi.org/10.1093/nar/gkw258

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