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Rational engineering of the Neurospora VS ribozyme to allow substrate recognition via different kissing-loop interactions

The Neurospora VS ribozyme is a catalytic RNA that has the unique ability to specifically recognize and cleave a stem-loop substrate through formation of a highly stable kissing-loop interaction (KLI). In order to explore the engineering potential of the VS ribozyme to cleave alternate substrates, w...

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Detalles Bibliográficos
Autores principales:	Lacroix-Labonté, Julie, Girard, Nicolas, Dagenais, Pierre, Legault, Pascale
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001590/ https://www.ncbi.nlm.nih.gov/pubmed/27166370 http://dx.doi.org/10.1093/nar/gkw401

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