FANCJ is essential to maintain microsatellite structure genome-wide during replication stress

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Microsatellite DNAs that form non-B structures are implicated in replication fork stalling, DNA double strand breaks (DSBs) and human disease. Fanconi anemia (FA) is an inherited disorder in which mutations in at least nineteen genes are responsible for the phenotypes of genome instability and cance...

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Detalles Bibliográficos
Autores principales: Barthelemy, Joanna, Hanenberg, Helmut, Leffak, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001596/
https://www.ncbi.nlm.nih.gov/pubmed/27179029
http://dx.doi.org/10.1093/nar/gkw433

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