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Conformational selection and dynamic adaptation upon linker histone binding to the nucleosome

Linker histones are essential for DNA compaction in chromatin. They bind to nucleosomes in a 1:1 ratio forming chromatosomes. Alternative configurations have been proposed in which the globular domain of the linker histone H5 (gH5) is positioned either on- or off-dyad between the nucleosomal and lin...

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Detalles Bibliográficos
Autores principales: Öztürk, Mehmet Ali, Pachov, Georgi V., Wade, Rebecca C., Cojocaru, Vlad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001602/
https://www.ncbi.nlm.nih.gov/pubmed/27270081
http://dx.doi.org/10.1093/nar/gkw514