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Distinct types of translation termination generate substrates for ribosome-associated quality control

Cotranslational degradation of polypeptide nascent chains plays a critical role in quality control of protein synthesis and the rescue of stalled ribosomes. In eukaryotes, ribosome stalling triggers release of 60S subunits with attached nascent polypeptides, which undergo ubiquitination by the E3 li...

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Detalles Bibliográficos
Autores principales:	Shcherbik, Natalia, Chernova, Tatiana A., Chernoff, Yury O., Pestov, Dimitri G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001609/ https://www.ncbi.nlm.nih.gov/pubmed/27325745 http://dx.doi.org/10.1093/nar/gkw566

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