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Multiple P-TEFbs cooperatively regulate the release of promoter-proximally paused RNA polymerase II

The association of DSIF and NELF with initiated RNA Polymerase II (Pol II) is the general mechanism for inducing promoter-proximal pausing of Pol II. However, it remains largely unclear how the paused Pol II is released in response to stimulation. Here, we show that the release of the paused Pol II...

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Detalles Bibliográficos
Autores principales: Lu, Xiaodong, Zhu, Xinxing, Li, You, Liu, Min, Yu, Bin, Wang, Yu, Rao, Muhua, Yang, Haiyang, Zhou, Kai, Wang, Yao, Chen, Yanheng, Chen, Meihua, Zhuang, Songkuan, Chen, Lin-Feng, Liu, Runzhong, Chen, Ruichuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001612/
https://www.ncbi.nlm.nih.gov/pubmed/27353326
http://dx.doi.org/10.1093/nar/gkw571