Triheptanoin Protects Motor Neurons and Delays the Onset of Motor Symptoms in a Mouse Model of Amyotrophic Lateral Sclerosis

There is increasing evidence that energy metabolism is disturbed in Amyotrophic Lateral Sclerosis (ALS) patients and animal models. Treatment with triheptanoin, the triglyceride of heptanoate, is a promising approach to provide alternative fuel to improve oxidative phosphorylation and aid ATP genera...

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Detalles Bibliográficos
Autores principales: Tefera, Tesfaye W., Wong, Yide, Barkl-Luke, Mallory E., Ngo, Shyuan T., Thomas, Nicola K., McDonald, Tanya S., Borges, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001695/
https://www.ncbi.nlm.nih.gov/pubmed/27564703
http://dx.doi.org/10.1371/journal.pone.0161816

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