Regulation of C3 Activation by the Alternative Complement Pathway in the Mouse Retina

The purpose of this study was to examine the retinas of mice carrying hemizygous and null double deletions of Cfb(-/-) and Cfh(-/-), and to compare these with the single knockouts of Cfb, Cfh and Cfd. Retinas were isolated from wild type (WT), Cfb(-/-)/Cfh(-/-), Cfb(-/-)/Cfh(+/-), Cfh(-/-)/Cfb(+/-),...

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Detalles Bibliográficos
Autores principales: Williams, Jennifer A. E., Stampoulis, Dimitris, Gunter, Chloe E., Greenwood, John, Adamson, Peter, Moss, Stephen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001704/
https://www.ncbi.nlm.nih.gov/pubmed/27564415
http://dx.doi.org/10.1371/journal.pone.0161898

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