Mg(2+) Extrusion from Intestinal Epithelia by CNNM Proteins Is Essential for Gonadogenesis via AMPK-TORC1 Signaling in Caenorhabditis elegans

Mg(2+) serves as an essential cofactor for numerous enzymes and its levels are tightly regulated by various Mg(2+) transporters. Here, we analyzed Caenorhabditis elegans strains carrying mutations in genes encoding cyclin M (CNNM) Mg(2+) transporters. We isolated inactivating mutants for each of the...

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Detalles Bibliográficos
Autores principales: Ishii, Tasuku, Funato, Yosuke, Hashizume, Osamu, Yamazaki, Daisuke, Hirata, Yusuke, Nishiwaki, Kiyoji, Kono, Nozomu, Arai, Hiroyuki, Miki, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001713/
https://www.ncbi.nlm.nih.gov/pubmed/27564576
http://dx.doi.org/10.1371/journal.pgen.1006276

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