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Intra-articular injection of two different doses of autologous bone marrow mesenchymal stem cells versus hyaluronic acid in the treatment of knee osteoarthritis: multicenter randomized controlled clinical trial (phase I/II)
BACKGROUND: Mesenchymal stromal cells are a promising option to treat knee osteoarthritis. Their safety and usefulness must be confirmed and the optimal dose established. We tested increasing doses of bone marrow mesenchymal stromal cells (BM-MSCs) in combination with hyaluronic acid in a randomized...
Autores principales: | Lamo-Espinosa, José M., Mora, Gonzalo, Blanco, Juan F., Granero-Moltó, Froilán, Nuñez-Córdoba, Jorge M., Sánchez-Echenique, Carmen, Bondía, José M., Aquerreta, Jesús Dámaso, Andreu, Enrique J., Ornilla, Enrique, Villarón, Eva M., Valentí-Azcárate, Andrés, Sánchez-Guijo, Fermín, del Cañizo, María Consuelo, Valentí-Nin, Juan Ramón, Prósper, Felipe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002157/ https://www.ncbi.nlm.nih.gov/pubmed/27565858 http://dx.doi.org/10.1186/s12967-016-0998-2 |
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