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Proton-pump inhibitor omeprazole attenuates hyperoxia induced lung injury

BACKGROUND: The administration of supplemental oxygen to treat ventilatory insufficiency may lead to the formation of reactive oxygen species and subsequent tissue damage. Cytochrome P4501A1 (CYP1A1) can modulate hyperoxic lung injury by a currently unknown mechanism. Our objective was to evaluate t...

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Detalles Bibliográficos
Autores principales:	Richter, Jute, Jimenez, Julio, Nagatomo, Taro, Toelen, Jaan, Brady, Paul, Salaets, Thomas, Lesage, Flore, Vanoirbeek, Jeroen, Deprest, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002203/ https://www.ncbi.nlm.nih.gov/pubmed/27567616 http://dx.doi.org/10.1186/s12967-016-1009-3

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