An opportunistic study evaluating pharmacokinetics of sildenafil for the treatment of pulmonary hypertension in infants

OBJECTIVE: To assess sildenafil and N-desmethyl sildenafil (DMS) exposure in infants receiving sildenafil for the treatment of pulmonary hypertension (PH). STUDY DESIGN: Data were collected from 6 infants receiving sildenafil for the treatment of PH, and plasma samples were collected at the time of...

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Detalles Bibliográficos
Autores principales: Thakkar, Nilay, Gonzalez, Daniel, Cohen-Wolkowiez, Michael, Massaro, Matthew, Bernhardt, Janice, Zane, Nicole R., Laughon, Matthew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002251/
https://www.ncbi.nlm.nih.gov/pubmed/27171763
http://dx.doi.org/10.1038/jp.2016.79

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002251/
https://www.ncbi.nlm.nih.gov/pubmed/27171763
http://dx.doi.org/10.1038/jp.2016.79

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