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Free Energy Landscape of Lipid Interactions with Regulatory Binding Sites on the Transmembrane Domain of the EGF Receptor

[Image: see text] Lipid molecules can bind to specific sites on integral membrane proteins, modulating their structure and function. We have undertaken coarse-grained simulations to calculate free energy profiles for glycolipids and phospholipids interacting with modulatory sites on the transmembran...

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Detalles Bibliográficos
Autores principales:	Hedger, George, Shorthouse, David, Koldsø, Heidi, Sansom, Mark S. P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2016
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002933/ https://www.ncbi.nlm.nih.gov/pubmed/27109430 http://dx.doi.org/10.1021/acs.jpcb.6b01387

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