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The epidemiology, healthcare and societal burden and costs of asthma in the UK and its member nations: analyses of standalone and linked national databases

BACKGROUND: There are a lack of reliable data on the epidemiology and associated burden and costs of asthma. We sought to provide the first UK-wide estimates of the epidemiology, healthcare utilisation and costs of asthma. METHODS: We obtained and analysed asthma-relevant data from 27 datasets: thes...

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Autores principales: Mukherjee, Mome, Stoddart, Andrew, Gupta, Ramyani P., Nwaru, Bright I., Farr, Angela, Heaven, Martin, Fitzsimmons, Deborah, Bandyopadhyay, Amrita, Aftab, Chantelle, Simpson, Colin R., Lyons, Ronan A., Fischbacher, Colin, Dibben, Christopher, Shields, Michael D., Phillips, Ceri J., Strachan, David P., Davies, Gwyneth A., McKinstry, Brian, Sheikh, Aziz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002970/
https://www.ncbi.nlm.nih.gov/pubmed/27568881
http://dx.doi.org/10.1186/s12916-016-0657-8
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author Mukherjee, Mome
Stoddart, Andrew
Gupta, Ramyani P.
Nwaru, Bright I.
Farr, Angela
Heaven, Martin
Fitzsimmons, Deborah
Bandyopadhyay, Amrita
Aftab, Chantelle
Simpson, Colin R.
Lyons, Ronan A.
Fischbacher, Colin
Dibben, Christopher
Shields, Michael D.
Phillips, Ceri J.
Strachan, David P.
Davies, Gwyneth A.
McKinstry, Brian
Sheikh, Aziz
author_facet Mukherjee, Mome
Stoddart, Andrew
Gupta, Ramyani P.
Nwaru, Bright I.
Farr, Angela
Heaven, Martin
Fitzsimmons, Deborah
Bandyopadhyay, Amrita
Aftab, Chantelle
Simpson, Colin R.
Lyons, Ronan A.
Fischbacher, Colin
Dibben, Christopher
Shields, Michael D.
Phillips, Ceri J.
Strachan, David P.
Davies, Gwyneth A.
McKinstry, Brian
Sheikh, Aziz
author_sort Mukherjee, Mome
collection PubMed
description BACKGROUND: There are a lack of reliable data on the epidemiology and associated burden and costs of asthma. We sought to provide the first UK-wide estimates of the epidemiology, healthcare utilisation and costs of asthma. METHODS: We obtained and analysed asthma-relevant data from 27 datasets: these comprised national health surveys for 2010–11, and routine administrative, health and social care datasets for 2011–12; 2011–12 costs were estimated in pounds sterling using economic modelling. RESULTS: The prevalence of asthma depended on the definition and data source used. The UK lifetime prevalence of patient-reported symptoms suggestive of asthma was 29.5 % (95 % CI, 27.7–31.3; n = 18.5 million (m) people) and 15.6 % (14.3–16.9, n = 9.8 m) for patient-reported clinician-diagnosed asthma. The annual prevalence of patient-reported clinician-diagnosed-and-treated asthma was 9.6 % (8.9–10.3, n = 6.0 m) and of clinician-reported, diagnosed-and-treated asthma 5.7 % (5.7–5.7; n = 3.6 m). Asthma resulted in at least 6.3 m primary care consultations, 93,000 hospital in-patient episodes, 1800 intensive-care unit episodes and 36,800 disability living allowance claims. The costs of asthma were estimated at least £1.1 billion: 74 % of these costs were for provision of primary care services (60 % prescribing, 14 % consultations), 13 % for disability claims, and 12 % for hospital care. There were 1160 asthma deaths. CONCLUSIONS: Asthma is very common and is responsible for considerable morbidity, healthcare utilisation and financial costs to the UK public sector. Greater policy focus on primary care provision is needed to reduce the risk of asthma exacerbations, hospitalisations and deaths, and reduce costs. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12916-016-0657-8) contains supplementary material, which is available to authorized users.
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spelling pubmed-50029702016-08-30 The epidemiology, healthcare and societal burden and costs of asthma in the UK and its member nations: analyses of standalone and linked national databases Mukherjee, Mome Stoddart, Andrew Gupta, Ramyani P. Nwaru, Bright I. Farr, Angela Heaven, Martin Fitzsimmons, Deborah Bandyopadhyay, Amrita Aftab, Chantelle Simpson, Colin R. Lyons, Ronan A. Fischbacher, Colin Dibben, Christopher Shields, Michael D. Phillips, Ceri J. Strachan, David P. Davies, Gwyneth A. McKinstry, Brian Sheikh, Aziz BMC Med Research Article BACKGROUND: There are a lack of reliable data on the epidemiology and associated burden and costs of asthma. We sought to provide the first UK-wide estimates of the epidemiology, healthcare utilisation and costs of asthma. METHODS: We obtained and analysed asthma-relevant data from 27 datasets: these comprised national health surveys for 2010–11, and routine administrative, health and social care datasets for 2011–12; 2011–12 costs were estimated in pounds sterling using economic modelling. RESULTS: The prevalence of asthma depended on the definition and data source used. The UK lifetime prevalence of patient-reported symptoms suggestive of asthma was 29.5 % (95 % CI, 27.7–31.3; n = 18.5 million (m) people) and 15.6 % (14.3–16.9, n = 9.8 m) for patient-reported clinician-diagnosed asthma. The annual prevalence of patient-reported clinician-diagnosed-and-treated asthma was 9.6 % (8.9–10.3, n = 6.0 m) and of clinician-reported, diagnosed-and-treated asthma 5.7 % (5.7–5.7; n = 3.6 m). Asthma resulted in at least 6.3 m primary care consultations, 93,000 hospital in-patient episodes, 1800 intensive-care unit episodes and 36,800 disability living allowance claims. The costs of asthma were estimated at least £1.1 billion: 74 % of these costs were for provision of primary care services (60 % prescribing, 14 % consultations), 13 % for disability claims, and 12 % for hospital care. There were 1160 asthma deaths. CONCLUSIONS: Asthma is very common and is responsible for considerable morbidity, healthcare utilisation and financial costs to the UK public sector. Greater policy focus on primary care provision is needed to reduce the risk of asthma exacerbations, hospitalisations and deaths, and reduce costs. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12916-016-0657-8) contains supplementary material, which is available to authorized users. BioMed Central 2016-08-29 /pmc/articles/PMC5002970/ /pubmed/27568881 http://dx.doi.org/10.1186/s12916-016-0657-8 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Mukherjee, Mome
Stoddart, Andrew
Gupta, Ramyani P.
Nwaru, Bright I.
Farr, Angela
Heaven, Martin
Fitzsimmons, Deborah
Bandyopadhyay, Amrita
Aftab, Chantelle
Simpson, Colin R.
Lyons, Ronan A.
Fischbacher, Colin
Dibben, Christopher
Shields, Michael D.
Phillips, Ceri J.
Strachan, David P.
Davies, Gwyneth A.
McKinstry, Brian
Sheikh, Aziz
The epidemiology, healthcare and societal burden and costs of asthma in the UK and its member nations: analyses of standalone and linked national databases
title The epidemiology, healthcare and societal burden and costs of asthma in the UK and its member nations: analyses of standalone and linked national databases
title_full The epidemiology, healthcare and societal burden and costs of asthma in the UK and its member nations: analyses of standalone and linked national databases
title_fullStr The epidemiology, healthcare and societal burden and costs of asthma in the UK and its member nations: analyses of standalone and linked national databases
title_full_unstemmed The epidemiology, healthcare and societal burden and costs of asthma in the UK and its member nations: analyses of standalone and linked national databases
title_short The epidemiology, healthcare and societal burden and costs of asthma in the UK and its member nations: analyses of standalone and linked national databases
title_sort epidemiology, healthcare and societal burden and costs of asthma in the uk and its member nations: analyses of standalone and linked national databases
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002970/
https://www.ncbi.nlm.nih.gov/pubmed/27568881
http://dx.doi.org/10.1186/s12916-016-0657-8
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