The rate of protein synthesis in hematopoietic stem cells is limited partly by 4E-BPs

Adult stem cells must limit their rate of protein synthesis, but the underlying mechanisms remain largely unexplored. Differences in protein synthesis among hematopoietic stem cells (HSCs) and progenitor cells did not correlate with differences in proteasome activity, total RNA content, mRNA content...

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Detalles Bibliográficos
Autores principales: Signer, Robert A.J., Qi, Le, Zhao, Zhiyu, Thompson, David, Sigova, Alla A., Fan, Zi Peng, DeMartino, George N., Young, Richard A., Sonenberg, Nahum, Morrison, Sean J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002975/
https://www.ncbi.nlm.nih.gov/pubmed/27492367
http://dx.doi.org/10.1101/gad.282756.116

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