Preclinical evaluation of mesenchymal stem cells overexpressing VEGF to treat critical limb ischemia

Numerous clinical trials are utilizing mesenchymal stem cells (MSC) to treat critical limb ischemia, primarily for their ability to secrete signals that promote revascularization. These cells have demonstrated clinical safety, but their efficacy has been limited, possibly because these paracrine sig...

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Detalles Bibliográficos
Autores principales: Beegle, Julie R, Magner, Nataly Lessa, Kalomoiris, Stefanos, Harding, Aja, Zhou, Ping, Nacey, Catherine, White, Jeannine Logan, Pepper, Karen, Gruenloh, William, Annett, Geralyn, Nolta, Jan A, Fierro, Fernando A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003097/
https://www.ncbi.nlm.nih.gov/pubmed/27610394
http://dx.doi.org/10.1038/mtm.2016.53

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