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Diminazene Aceturate Improves Cardiac Fibrosis and Diastolic Dysfunction in Rats with Kidney Disease

Angiotensin converting enzyme (ACE) 2 is a negative regulator of the renin angiotensin system (RAS) through its role to degrade angiotensin II. In rats with subtotal nephrectomy (STNx), adverse cardiac remodelling occurs despite elevated cardiac ACE2 activity. We hypothesised that diminazene acetura...

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Detalles Bibliográficos
Autores principales:	Velkoska, Elena, Patel, Sheila K., Griggs, Karen, Burrell, Louise M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003360/ https://www.ncbi.nlm.nih.gov/pubmed/27571511 http://dx.doi.org/10.1371/journal.pone.0161760

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