Design, synthesis, and characterization of (1-(4-aryl)- 1H-1,2,3-triazol-4-yl)methyl, substituted phenyl-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylates against Mycobacterium tuberculosis

The novel (1-(4-aryl)-1H-1,2,3-triazol-4-yl)methyl, substituted phenyl-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate derivatives were synthesized by the click reaction of the dihydropyrimidinones, bearing a terminal alkynyl group, with various substituted aryl azides at room temperature...

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Detalles Bibliográficos
Autores principales: Venugopala, Katharigatta N, Dharma Rao, G B, Bhandary, Subhrajyoti, Pillay, Melendhran, Chopra, Deepak, Aldhubiab, Bandar E, Attimarad, Mahesh, Alwassil, Osama Ibrahim, Harsha, Sree, Mlisana, Koleka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003518/
https://www.ncbi.nlm.nih.gov/pubmed/27601885
http://dx.doi.org/10.2147/DDDT.S109760

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