Novel matrine derivative MD-1 attenuates hepatic fibrosis by inhibiting EGFR activation of hepatic stellate cells

Matrine (MT), the effective component of Sophora flavescens Ait, has been shown to have anti-inflammation, immune-suppressive, anti-tumor, and anti-hepatic fibrosis activities. However, the pharmacological effects of MT still need to be strengthened due to its relatively low efficacy and short half-...

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Detalles Bibliográficos
Autores principales: Feng, Yi, Ying, Hai-yan, Qu, Ying, Cai, Xiao-bo, Xu, Ming-yi, Lu, Lun-gen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003784/
https://www.ncbi.nlm.nih.gov/pubmed/27342773
http://dx.doi.org/10.1007/s13238-016-0285-2

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