Cargando…

Characterization of Cellular and Molecular Heterogeneity of Bone Marrow Stromal Cells

Human bone marrow-derived stromal stem cells (hBMSC) exhibit multiple functions, including differentiation into skeletal cells (progenitor function), hematopoiesis support, and immune regulation (nonprogenitor function). We have previously demonstrated the presence of morphological and functional he...

Descripción completa

Detalles Bibliográficos
Autores principales:	Elsafadi, Mona, Manikandan, Muthurangan, Atteya, Muhammad, Hashmi, Jamil Amjad, Iqbal, Zafar, Aldahmash, Abdullah, Alfayez, Musaad, Kassem, Moustapha, Mahmood, Amer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004045/ https://www.ncbi.nlm.nih.gov/pubmed/27610142 http://dx.doi.org/10.1155/2016/9378081

Ejemplares similares

Convergence of TGFβ and BMP signaling in regulating human bone marrow stromal cell differentiation
por: Elsafadi, Mona, et al.
Publicado: (2019)

SERPINB2 is a novel TGFβ-responsive lineage fate determinant of human bone marrow stromal cells
por: Elsafadi, Mona, et al.
Publicado: (2017)

Author Correction: Convergence of TGFβ and BMP signaling in regulating human bone marrow stromal cell differentiation
por: Elsafadi, Mona, et al.
Publicado: (2019)

Author Correction: Convergence of TGFβ and BMP signaling in regulating human bone marrow stromal cell differentiation
por: Elsafadi, Mona, et al.
Publicado: (2023)

TGFβ1-Induced Differentiation of Human Bone Marrow-Derived MSCs Is Mediated by Changes to the Actin Cytoskeleton
por: Elsafadi, Mona, et al.
Publicado: (2018)

Transgelin is a poor prognostic factor associated with advanced colorectal cancer (CRC) stage promoting tumor growth and migration in a TGFβ-dependent manner
por: Elsafadi, Mona, et al.
Publicado: (2020)

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
por: AlMuraikhi, Nihal, et al.
Publicado: (2019)

Neoplastic Transformation of Human Mesenchymal Stromal Cells Mediated via LIN28B
por: Vishnubalaji, Radhakrishnan, et al.
Publicado: (2019)

Stem cell library screen identified ruxolitinib as regulator of osteoblastic differentiation of human skeletal stem cells
por: AlMuraikhi, Nihal, et al.
Publicado: (2018)

Molecular profiling of ALDH1(+) colorectal cancer stem cells reveals preferential activation of MAPK, FAK, and oxidative stress pro-survival signalling pathways
por: Vishnubalaji, Radhakrishnan, et al.
Publicado: (2018)

Romidepsin Promotes Osteogenic and Adipocytic Differentiation of Human Mesenchymal Stem Cells through Inhibition of Histondeacetylase Activity
por: Ali, Dalia, et al.
Publicado: (2018)

Hedgehog Signaling Inhibition by Smoothened Antagonist BMS-833923 Reduces Osteoblast Differentiation and Ectopic Bone Formation of Human Skeletal (Mesenchymal) Stem Cells
por: AlMuraikhi, Nihal, et al.
Publicado: (2019)

Multiple intracellular signaling pathways orchestrate adipocytic differentiation of human bone marrow stromal stem cells
por: Ali, Dalia, et al.
Publicado: (2018)

MicroRNA-3148 acts as molecular switch promoting malignant transformation and adipocytic differentiation of immortalized human bone marrow stromal cells via direct targeting of the SMAD2/TGFβ pathway
por: Vishnubalaji, Radhakrishnan, et al.
Publicado: (2020)

Whole genome mRNA expression profiling revealed multiple deregulated pathways in stromal vascular fraction from erectile dysfunction patients
por: Vishnubalaji, Radhakrishnan, et al.
Publicado: (2018)

CXCR7 signaling promotes breast cancer survival in response to mesenchymal stromal stem cell-derived factors
por: Al-toub, Mashael, et al.
Publicado: (2019)

Cytotoxicity of QMix™ endodontic irrigating solution on human bone marrow mesenchymal stem cells
por: AlKahtani, Ahmad, et al.
Publicado: (2014)

Tankyrase inhibitor XAV-939 enhances osteoblastogenesis and mineralization of human skeletal (mesenchymal) stem cells
por: Almasoud, Nuha, et al.
Publicado: (2020)

Author Correction: Tankyrase inhibitor XAV-939 enhances osteoblastogenesis and mineralization of human skeletal (mesenchymal) stem cells
por: Almasoud, Nuha, et al.
Publicado: (2021)

Transgelin is a TGFβ-inducible gene that regulates osteoblastic and adipogenic differentiation of human skeletal stem cells through actin cytoskeleston organization
por: Elsafadi, M, et al.
Publicado: (2016)

Bone morphogenetic protein 2 (BMP2) induces growth suppression and enhances chemosensitivity of human colon cancer cells
por: Vishnubalaji, Radhakrishnan, et al.
Publicado: (2016)

Concurrent targeting of BMI1 and CDK4/6 abrogates tumor growth in vitro and in vivo
por: Elango, Ramesh, et al.
Publicado: (2019)

Effects of all-trans retinoic acid on the in vitro maturation of camel (Camelus dromedarius) cumulus-oocyte complexes
por: SAADELDIN, Islam M., et al.
Publicado: (2019)

Circulating microRNAs in breast cancer: novel diagnostic and prognostic biomarkers
por: Hamam, Rimi, et al.
Publicado: (2017)

In vitro differentiation of human skin-derived multipotent stromal cells into putative endothelial-like cells
por: Vishnubalaji, Radhakrishnan, et al.
Publicado: (2012)

Cytotoxicity of Different Concentrations of Three Root Canal Sealers on Human Mesenchymal Stem Cells
por: Alsubait, Sara A., et al.
Publicado: (2018)

Thermotolerance and plasticity of camel somatic cells exposed to acute and chronic heat stress
por: Saadeldin, Islam M., et al.
Publicado: (2019)

Molecular characterisation of stromal populations derived from human embryonic stem cells: Similarities to immortalised bone marrow derived stromal stem cells
por: Harkness, Linda, et al.
Publicado: (2015)

Human Stromal (Mesenchymal) Stem Cells: Basic Biology and Current Clinical Use for Tissue Regeneration
por: Aldahmash, Abdullah, et al.
Publicado: (2012)

MicroRNA Expression Profiling on Paired Primary and Lymph Node Metastatic Breast Cancer Revealed Distinct microRNA Profile Associated With LNM
por: Elango, Ramesh, et al.
Publicado: (2020)

Inhibition of GSK-3β Enhances Osteoblast Differentiation of Human Mesenchymal Stem Cells through Wnt Signalling Overexpressing Runx2
por: AlMuraikhi, Nihal, et al.
Publicado: (2023)

The Bone Marrow-Derived Stromal Cells: Commitment and Regulation of Adipogenesis
por: Tencerova, Michaela, et al.
Publicado: (2016)

Human Stromal (Mesenchymal) Stem Cells from Bone Marrow, Adipose Tissue and Skin Exhibit Differences in Molecular Phenotype and Differentiation Potential
por: Al-Nbaheen, May, et al.
Publicado: (2012)

ACI/EG eutectic mixture mediated synthesis, characterization and in vitro osteoblast differentiation assessment of spiropyrrolo[1,2-b]isoquinoline analogues
por: Periyasami, Govindasami, et al.
Publicado: (2018)

microRNA expression profiling on individual breast cancer patients identifies novel panel of circulating microRNA for early detection
por: Hamam, Rimi, et al.
Publicado: (2016)

Molecular Phenotyping of Telomerized Human Bone Marrow Skeletal Stem Cells Reveals a Genetic Program of Enhanced Proliferation and Maintenance of Differentiation Responses
por: Twine, Natalie A, et al.
Publicado: (2018)

Pleiotropic effects of cancer cells’ secreted factors on human stromal (mesenchymal) stem cells
por: Al-toub, Mashael, et al.
Publicado: (2013)

JAK2 Inhibition by Fedratinib Reduces Osteoblast Differentiation and Mineralisation of Human Mesenchymal Stem Cells
por: AlMuraikhi, Nihal, et al.
Publicado: (2021)

Angiogenic Potential of Human Neonatal Foreskin Stromal Cells in the Chick Embryo Chorioallantoic Membrane Model
por: Vishnubalaji, Radhakrishnan, et al.
Publicado: (2015)

Induction of primitive streak and mesendoderm formation in monolayer hESC culture by activation of TGF-β signaling pathway by Activin B
por: Mahmood, Amer, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_e00t9bnkdd0ahna9e4dvqb4bap