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Hyperuricemia in acute gastroenteritis is caused by decreased urate excretion via ABCG2

To clarify the physiological and pathophysiological roles of intestinal urate excretion via ABCG2 in humans, we genotyped ABCG2 dysfunctional common variants, Q126X (rs72552713) and Q141K (rs2231142), in end-stage renal disease (hemodialysis) and acute gastroenteritis patients, respectively. ABCG2 d...

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Detalles Bibliográficos
Autores principales:	Matsuo, Hirotaka, Tsunoda, Tomoyuki, Ooyama, Keiko, Sakiyama, Masayuki, Sogo, Tsuyoshi, Takada, Tappei, Nakashima, Akio, Nakayama, Akiyoshi, Kawaguchi, Makoto, Higashino, Toshihide, Wakai, Kenji, Ooyama, Hiroshi, Hokari, Ryota, Suzuki, Hiroshi, Ichida, Kimiyoshi, Inui, Ayano, Fujimori, Shin, Shinomiya, Nariyoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004129/ https://www.ncbi.nlm.nih.gov/pubmed/27571712 http://dx.doi.org/10.1038/srep31003

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