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In silico modelling of a cancer stem cell-targeting agent and its effects on tumour control during radiotherapy
Head and neck cancers (HNC), like most solid tumours, contain a subpopulation of cancer stem cells (CSC) that are commonly responsible for treatment failure. Conventional therapies are unsuccessful in controlling CSCs, thus novel, targeting therapies are needed. A promising agent is ATRA (All-trans-...
Autores principales: | Marcu, Loredana G., Marcu, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004146/ https://www.ncbi.nlm.nih.gov/pubmed/27573059 http://dx.doi.org/10.1038/srep32332 |
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