Abcb1 in Pigs: Molecular cloning, tissues distribution, functional analysis, and its effect on pharmacokinetics of enrofloxacin

P-glycoprotein (P-gp) is one of the best-known ATP-dependent efflux transporters, contributing to differences in pharmacokinetics and drug-drug interactions. Until now, studies on pig P-gp have been scarce. In our studies, the full-length porcine P-gp cDNA was cloned and expressed in a Madin-Darby C...

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Detalles Bibliográficos
Autores principales: Guo, Tingting, Huang, Jinhu, Zhang, Hongyu, Dong, Lingling, Guo, Dawei, Guo, Li, He, Fang, Bhutto, Zohaib Ahmed, Wang, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004175/
https://www.ncbi.nlm.nih.gov/pubmed/27572343
http://dx.doi.org/10.1038/srep32244

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