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Role of Cathepsins in Mycobacterium tuberculosis Survival in Human Macrophages

Cathepsins are proteolytic enzymes that function in the endocytic pathway, especially in lysosomes, where they contribute directly to pathogen killing or indirectly, by their involvement in the antigen presentation pathways. Mycobacterium tuberculosis (MTB) is a facultative intracellular pathogen th...

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Detalles Bibliográficos
Autores principales:	Pires, David, Marques, Joana, Pombo, João Palma, Carmo, Nuno, Bettencourt, Paulo, Neyrolles, Olivier, Lugo-Villarino, Geanncarlo, Anes, Elsa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004184/ https://www.ncbi.nlm.nih.gov/pubmed/27572605 http://dx.doi.org/10.1038/srep32247

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