An integrated genetic-epigenetic analysis of schizophrenia: evidence for co-localization of genetic associations and differential DNA methylation

BACKGROUND: Schizophrenia is a highly heritable, neuropsychiatric disorder characterized by episodic psychosis and altered cognitive function. Despite success in identifying genetic variants associated with schizophrenia, there remains uncertainty about the causal genes involved in disease pathogene...

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Detalles Bibliográficos
Autores principales: Hannon, Eilis, Dempster, Emma, Viana, Joana, Burrage, Joe, Smith, Adam R., Macdonald, Ruby, St Clair, David, Mustard, Colette, Breen, Gerome, Therman, Sebastian, Kaprio, Jaakko, Toulopoulou, Timothea, Pol, Hilleke E. Hulshoff, Bohlken, Marc M., Kahn, Rene S., Nenadic, Igor, Hultman, Christina M., Murray, Robin M., Collier, David A., Bass, Nick, Gurling, Hugh, McQuillin, Andrew, Schalkwyk, Leonard, Mill, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004279/
https://www.ncbi.nlm.nih.gov/pubmed/27572077
http://dx.doi.org/10.1186/s13059-016-1041-x

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