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Mapping an epitope in EBNA‐1 that is recognized by monoclonal antibodies to EBNA‐1 that cross‐react with dsDNA

INTRODUCTION: The Epstein Barr Virus (EBV) has been associated with the autoimmune disease, Systemic Lupus Erythematosus (SLE). EBV nuclear antigen‐I (EBNA‐1) is the major nuclear protein of EBV. We previously generated an IgG monoclonal antibody (MAb) to EBNA‐1, 3D4, and demonstrated that it cross‐...

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Detalles Bibliográficos
Autores principales: Yadav, Pragya, Carr, Matthew T., Yu, Ruby, Mumbey‐Wafula, Alice, Spatz, Linda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004290/
https://www.ncbi.nlm.nih.gov/pubmed/27621818
http://dx.doi.org/10.1002/iid3.119

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