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An siRNA screen for ATG protein depletion reveals the extent of the unconventional functions of the autophagy proteome in virus replication
Autophagy is a catabolic process regulated by the orchestrated action of the autophagy-related (ATG) proteins. Recent work indicates that some of the ATG proteins also have autophagy-independent roles. Using an unbiased siRNA screen approach, we explored the extent of these unconventional functions...
Autores principales: | Mauthe, Mario, Langereis, Martijn, Jung, Jennifer, Zhou, Xingdong, Jones, Alex, Omta, Wienand, Tooze, Sharon A., Stork, Björn, Paludan, Søren Riis, Ahola, Tero, Egan, Dave, Behrends, Christian, Mokry, Michal, de Haan, Cornelis, van Kuppeveld, Frank, Reggiori, Fulvio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004442/ https://www.ncbi.nlm.nih.gov/pubmed/27573464 http://dx.doi.org/10.1083/jcb.201602046 |
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