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RhoA GTPase inhibition organizes contraction during epithelial morphogenesis

During morphogenesis, contraction of the actomyosin cytoskeleton within individual cells drives cell shape changes that fold tissues. Coordination of cytoskeletal contractility is mediated by regulating RhoA GTPase activity. Guanine nucleotide exchange factors (GEFs) activate and GTPase-activating p...

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Detalles Bibliográficos
Autores principales: Mason, Frank M., Xie, Shicong, Vasquez, Claudia G., Tworoger, Michael, Martin, Adam C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004446/
https://www.ncbi.nlm.nih.gov/pubmed/27551058
http://dx.doi.org/10.1083/jcb.201603077