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A PP2A-B55 recognition signal controls substrate dephosphorylation kinetics during mitotic exit
PP2A-B55 is one of the major phosphatases regulating cell division. Despite its importance for temporal control during mitotic exit, how B55 substrates are recognized and differentially dephosphorylated is unclear. Using phosphoproteomics combined with kinetic modeling to extract B55-dependent rate...
Autores principales: | Cundell, Michael J., Hutter, Lukas H., Nunes Bastos, Ricardo, Poser, Elena, Holder, James, Mohammed, Shabaz, Novak, Bela, Barr, Francis A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004449/ https://www.ncbi.nlm.nih.gov/pubmed/27551054 http://dx.doi.org/10.1083/jcb.201606033 |
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