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Cycling Rho for tissue contraction
Cell contractility, driven by the RhoA GTPase, is a fundamental determinant of tissue morphogenesis. In this issue, Mason et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201603077) reveal that cyclic inactivation of RhoA, mediated by its antagonist, C-GAP, is essential for effective contra...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004450/ https://www.ncbi.nlm.nih.gov/pubmed/27551059 http://dx.doi.org/10.1083/jcb.201608017 |
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author | Teo, Jessica L. Yap, Alpha S. |
author_facet | Teo, Jessica L. Yap, Alpha S. |
author_sort | Teo, Jessica L. |
collection | PubMed |
description | Cell contractility, driven by the RhoA GTPase, is a fundamental determinant of tissue morphogenesis. In this issue, Mason et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201603077) reveal that cyclic inactivation of RhoA, mediated by its antagonist, C-GAP, is essential for effective contractility to occur. |
format | Online Article Text |
id | pubmed-5004450 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-50044502017-02-28 Cycling Rho for tissue contraction Teo, Jessica L. Yap, Alpha S. J Cell Biol Commentary Cell contractility, driven by the RhoA GTPase, is a fundamental determinant of tissue morphogenesis. In this issue, Mason et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201603077) reveal that cyclic inactivation of RhoA, mediated by its antagonist, C-GAP, is essential for effective contractility to occur. The Rockefeller University Press 2016-08-29 /pmc/articles/PMC5004450/ /pubmed/27551059 http://dx.doi.org/10.1083/jcb.201608017 Text en © 2016 Teo and Yap This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/). |
spellingShingle | Commentary Teo, Jessica L. Yap, Alpha S. Cycling Rho for tissue contraction |
title | Cycling Rho for tissue contraction |
title_full | Cycling Rho for tissue contraction |
title_fullStr | Cycling Rho for tissue contraction |
title_full_unstemmed | Cycling Rho for tissue contraction |
title_short | Cycling Rho for tissue contraction |
title_sort | cycling rho for tissue contraction |
topic | Commentary |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004450/ https://www.ncbi.nlm.nih.gov/pubmed/27551059 http://dx.doi.org/10.1083/jcb.201608017 |
work_keys_str_mv | AT teojessical cyclingrhofortissuecontraction AT yapalphas cyclingrhofortissuecontraction |