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Inhibition of Human Cytochrome P450 2c8-catalyzed Amodiaquine N-desethylation: Effect of Five Traditionally and Commonly Used Herbs

BACKGROUND: In Southeast Asia and many parts of the world, herbal products are increasingly used in parallel with modern medicine. OBJECTIVE: This study aimed to investigate the effects of herbs commonly used in Southeast Asia on activity of cytochrome P450 2C8 (CYP2C8), an important human hepatic e...

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Detalles Bibliográficos
Autores principales: Muthiah, Yasotha Devi, Ong, Chin Eng, Sulaiman, Siti Amrah, Ismail, Rusli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004522/
https://www.ncbi.nlm.nih.gov/pubmed/27695271
http://dx.doi.org/10.4103/0974-8490.188886