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A novel hypoxia-induced miR-147a regulates cell proliferation through a positive feedback loop of stabilizing HIF-1α

Hypoxia is a general event in solid tumor growth. Therefore, induced cellular responses by hypoxia are important for tumorigenesis and tumor growth. MicroRNAs (miRNAs) have recently emerged as important regulators of hypoxia induced cellular responses. Here we report that miR-147a is a novel and cru...

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Detalles Bibliográficos
Autores principales: Wang, Fan, Zhang, Haoxiang, Xu, Naihan, Huang, Nunu, Tian, Caiming, Ye, Anlin, Hu, Guangnan, He, Jie, Zhang, Yaou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004686/
https://www.ncbi.nlm.nih.gov/pubmed/27260617
http://dx.doi.org/10.1080/15384047.2016.1195040