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Regulation of CpG methylation by Dnmt and Tet in pluripotent stem cells

Vertebrate genomes are highly methylated at cytosine residues in CpG sequences. CpG methylation plays an important role in epigenetic gene silencing and genome stability. Compared with other epigenetic modifications, CpG methylation is thought to be relatively stable; however, it is sometimes affect...

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Detalles Bibliográficos
Autores principales: HORII, Takuro, HATADA, Izuho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004787/
https://www.ncbi.nlm.nih.gov/pubmed/27151232
http://dx.doi.org/10.1262/jrd.2016-046

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