Nephron Progenitor But Not Stromal Progenitor Cells Give Rise to Wilms Tumors in Mouse Models with β-Catenin Activation or Wt1 Ablation and Igf2 Upregulation()

Wilms tumor, a common childhood tumor of the kidney, is thought to arise from undifferentiated renal mesenchyme. Variable tumor histology and the identification of tumor subsets displaying different gene expression profiles suggest that tumors may arise at different stages of mesenchyme differentiat...

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Detalles Bibliográficos
Autores principales: Huang, Le, Mokkapati, Sharada, Hu, Qianghua, Ruteshouser, E. Cristy, Hicks, M. John, Huff, Vicki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005262/
https://www.ncbi.nlm.nih.gov/pubmed/26936393
http://dx.doi.org/10.1016/j.neo.2015.12.001

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