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Post-transcriptional Regulation of BRCA2 through Interactions with miR-19a and miR-19b
Breast cancer type 2, early onset susceptibility gene (BRCA2) is a major component of the homologous recombination DNA repair pathway. It acts as a tumor suppressor whose function is often lost in cancers. Patients with specific mutations in the BRCA2 gene often display discrete clinical, histopatho...
Autores principales: | Mogilyansky, Elena, Clark, Peter, Quann, Kevin, Zhou, Honglei, Londin, Eric, Jing, Yi, Rigoutsos, Isidore |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005319/ https://www.ncbi.nlm.nih.gov/pubmed/27630665 http://dx.doi.org/10.3389/fgene.2016.00143 |
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