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Yellow Feet in a Patient with Breast and Thyroid Carcinoma, Due to Oral Intake of Turmeric
Yellow discoloration of the skin may be caused by several etiologies, including jaundice, hypervitaminosis, drug reaction or chemical exposure. Herein we describe a 68-year-old woman with a history of breast and thyroid carcinoma, presenting with a yellow discoloration of her soles, after ingestion...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005595/ https://www.ncbi.nlm.nih.gov/pubmed/27747716 http://dx.doi.org/10.1007/s40800-015-0006-4 |
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author | Horev, Liran Ramot, Yuval Klapholz, Laurent |
author_facet | Horev, Liran Ramot, Yuval Klapholz, Laurent |
author_sort | Horev, Liran |
collection | PubMed |
description | Yellow discoloration of the skin may be caused by several etiologies, including jaundice, hypervitaminosis, drug reaction or chemical exposure. Herein we describe a 68-year-old woman with a history of breast and thyroid carcinoma, presenting with a yellow discoloration of her soles, after ingestion of one capsule a day of turmeric root extract (Bluebonnet Turmeric Root, 500 mg, Vcap), taken for its anti-cancer properties, for 4 months. After drug cessation, the yellow hue disappeared completely. A Naranjo assessment score of 5 was obtained, indicating a probable relationship between the patient’s symptom and her use of the drug. Curcumin, a mixture of diferuloymethane derivatives known as curcuminoids, is a yellow pigment present in the spice turmeric. Topical application of curcumin to the human skin is joined by orange-yellow discoloration. To the best of our knowledge, yellow skin discoloration after oral intake of turmeric is not mentioned in the medical literature. |
format | Online Article Text |
id | pubmed-5005595 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-50055952016-08-31 Yellow Feet in a Patient with Breast and Thyroid Carcinoma, Due to Oral Intake of Turmeric Horev, Liran Ramot, Yuval Klapholz, Laurent Drug Saf Case Rep Case Report Yellow discoloration of the skin may be caused by several etiologies, including jaundice, hypervitaminosis, drug reaction or chemical exposure. Herein we describe a 68-year-old woman with a history of breast and thyroid carcinoma, presenting with a yellow discoloration of her soles, after ingestion of one capsule a day of turmeric root extract (Bluebonnet Turmeric Root, 500 mg, Vcap), taken for its anti-cancer properties, for 4 months. After drug cessation, the yellow hue disappeared completely. A Naranjo assessment score of 5 was obtained, indicating a probable relationship between the patient’s symptom and her use of the drug. Curcumin, a mixture of diferuloymethane derivatives known as curcuminoids, is a yellow pigment present in the spice turmeric. Topical application of curcumin to the human skin is joined by orange-yellow discoloration. To the best of our knowledge, yellow skin discoloration after oral intake of turmeric is not mentioned in the medical literature. Springer International Publishing 2015-03-26 /pmc/articles/PMC5005595/ /pubmed/27747716 http://dx.doi.org/10.1007/s40800-015-0006-4 Text en © The Author(s) 2015 https://creativecommons.org/licenses/by-nc/4.0/ Open AccessThis article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. |
spellingShingle | Case Report Horev, Liran Ramot, Yuval Klapholz, Laurent Yellow Feet in a Patient with Breast and Thyroid Carcinoma, Due to Oral Intake of Turmeric |
title | Yellow Feet in a Patient with Breast and Thyroid Carcinoma, Due to Oral Intake of Turmeric |
title_full | Yellow Feet in a Patient with Breast and Thyroid Carcinoma, Due to Oral Intake of Turmeric |
title_fullStr | Yellow Feet in a Patient with Breast and Thyroid Carcinoma, Due to Oral Intake of Turmeric |
title_full_unstemmed | Yellow Feet in a Patient with Breast and Thyroid Carcinoma, Due to Oral Intake of Turmeric |
title_short | Yellow Feet in a Patient with Breast and Thyroid Carcinoma, Due to Oral Intake of Turmeric |
title_sort | yellow feet in a patient with breast and thyroid carcinoma, due to oral intake of turmeric |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005595/ https://www.ncbi.nlm.nih.gov/pubmed/27747716 http://dx.doi.org/10.1007/s40800-015-0006-4 |
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