Association Between Autoantibodies Against Thyroid Stimulating Hormone Receptor and Thyroid Diseases

AIM: The aim of this study is to determine the relationship between TRAb and different diseases. The highest percentage of increased TRAb levels can be found at patients with Graves’ diseases. MATERIAL AND METHODS: Study was performed in 70 patients, grouped in three groups, and 14 persons who based on the clinical status and the levels of thyroid hormones do not have any thyroid disease. The TRAb levels has been determined in patients with Graves’ disease (N=40), Hashimoto’s disease (N=15), Plummer’s disease (N=15) and the control group (N=14). RESULTS: The highest mean TRAb levels exist in patients with Graves’ disease. There exists a positive correlation between TRAb levels and T3, and T4, while there is no correlation between TSH and TRAb levels in patients with Graves’ disease,. On the other hand, the correlation between TRAb and T3 and T4 in patients with Hashimoto’s diseases and Plummers disease was shown to be positive, but of a low levels.