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Bis-three-way junction nanostructure and DNA machineries for ultrasensitive and specific detection of BCR/ABL fusion gene by chemiluminescence imaging

A novel G-quadruplex DNAzyme-driven chemiluminescence (CL) imaging method has been developed for ultrasensitive and specific detection of BCR/ABL fusion gene based on bis-three-way junction (bis-3WJ) nanostructure and cascade DNA machineries. Bis-3WJ probes are designed logically to recognize BCR/AB...

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Detalles Bibliográficos
Autores principales: Xu, Yongjie, Bian, Xintong, Sang, Ye, Li, Yujian, Li, Dandan, Cheng, Wei, Yin, Yibing, Ju, Huangxian, Ding, Shijia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006031/
https://www.ncbi.nlm.nih.gov/pubmed/27577607
http://dx.doi.org/10.1038/srep32370

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