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Ultra-short laser-accelerated proton pulses have similar DNA-damaging effectiveness but produce less immediate nitroxidative stress than conventional proton beams

Ultra-short proton pulses originating from laser-plasma accelerators can provide instantaneous dose rates at least 10(7)-fold in excess of conventional, continuous proton beams. The impact of such extremely high proton dose rates on A549 human lung cancer cells was compared with conventionally accel...

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Detalles Bibliográficos
Autores principales: Raschke, S., Spickermann, S., Toncian, T., Swantusch, M., Boeker, J., Giesen, U., Iliakis, G., Willi, O., Boege, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006042/
https://www.ncbi.nlm.nih.gov/pubmed/27578260
http://dx.doi.org/10.1038/srep32441

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