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Cell types differ in global coordination of splicing and proportion of highly expressed genes

Balance in the transcriptome is regulated by coordinated synthesis and degradation of RNA molecules. Here we investigated whether mammalian cell types intrinsically differ in global coordination of gene splicing and expression levels. We analyzed RNA-seq transcriptome profiles of 8 different purifie...

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Detalles Bibliográficos
Autores principales: Trakhtenberg, Ephraim F., Pho, Nam, Holton, Kristina M., Chittenden, Thomas W., Goldberg, Jeffrey L., Dong, Lingsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006053/
https://www.ncbi.nlm.nih.gov/pubmed/27577089
http://dx.doi.org/10.1038/srep32249

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