Metabolite Analysis and Histology on the Exact Same Tissue: Comprehensive Metabolomic Profiling and Metabolic Classification of Prostate Cancer

We report a method of metabolomic profiling of intact tissue based on molecular preservation by extraction and fixation (mPREF) and high-performance chemical isotope labeling (CIL) liquid chromatography mass spectrometry (LC-MS). mPREF extracts metabolites by aqueous methanol from tissue biopsies wi...

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Detalles Bibliográficos
Autores principales: Huan, Tao, Troyer, Dean A., Li, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006072/
https://www.ncbi.nlm.nih.gov/pubmed/27578275
http://dx.doi.org/10.1038/srep32272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006072/
https://www.ncbi.nlm.nih.gov/pubmed/27578275
http://dx.doi.org/10.1038/srep32272

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