TRIM14 inhibits hepatitis C virus infection by SPRY domain-dependent targeted degradation of the viral NS5A protein

Tripartite motif 14 (TRIM14) was reported to function as a mitochondrial signaling adaptor in mediating innate immune responses. However, the involvement of TRIM14 in host defense against viral infection and molecular mechanisms remain unclear. Here, we demonstrated that enforced expression of TRIM1...

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Detalles Bibliográficos
Autores principales: Wang, Shanshan, Chen, Yongzhi, Li, Chunfeng, Wu, Yaoxing, Guo, Lei, Peng, Changwei, Huang, Yueping, Cheng, Genhong, Qin, F. Xiao-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006124/
https://www.ncbi.nlm.nih.gov/pubmed/27578425
http://dx.doi.org/10.1038/srep32336

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