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Pulmonary tumor thrombotic microangiopathy caused by prostate carcinoma

Pulmonary tumor thrombotic microangiopathy (PTTM) is a fatal malignancy-related condition that involves rapidly progressing hypoxia and pulmonary hypertension. We report a case of PTTM caused by prostate carcinoma, which was diagnosed before autopsy in an 81-year-old man. Computed tomography showed...

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Detalles Bibliográficos
Autores principales: Katayama, Daisuke, Kuriyama, Keiko, Kinoshita, Tatsuya, Nagai, Keisuke, Hongyo, Hidenari, Kishimoto, Kentaro, Inoue, Atsuo, Takamura, Manabu, Choi, Soomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006143/
https://www.ncbi.nlm.nih.gov/pubmed/27635254
http://dx.doi.org/10.1177/2058460116662300
Descripción
Sumario:Pulmonary tumor thrombotic microangiopathy (PTTM) is a fatal malignancy-related condition that involves rapidly progressing hypoxia and pulmonary hypertension. We report a case of PTTM caused by prostate carcinoma, which was diagnosed before autopsy in an 81-year-old man. Computed tomography showed diffuse ground-glass opacities, consolidation, and small nodules in the peripheral regions of the lung. Autopsy showed adenocarcinoma cells embolizing small pulmonary arteries with fibrocellular intimal proliferation, which was consistent with PTTM caused by prostate carcinoma.