Cargando…

Promising Nanocarriers for PEDF Gene Targeting Delivery to Cervical Cancer Cells Mediated by the Over-expressing FRα

Cervical cancer presents extremely low PEDF expression which is associated with tumor progression and poor prognosis. In this study, folate receptor α (FRα)-targeted nano-liposomes (FLP) were designed to enhance the anti-tumor effect by targeting delivery of exogenous PEDF gene to cervical cancer ce...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Yuhan, He, Lili, Liu, Yongmei, Xia, Shan, Fang, Aiping, Xie, Yafei, Gan, Li, He, Zhiyao, Tan, Xiaoyue, Jiang, Chunling, Tong, Aiping, Song, Xiangrong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006243/ https://www.ncbi.nlm.nih.gov/pubmed/27576898 http://dx.doi.org/10.1038/srep32427

Ejemplares similares

NANO-SBT-PEDF delivery system: A promising approach against ovarian cancer?
por: Ribaux, Pascale, et al.
Publicado: (2023)

Nanoliposome-Encapsulated Brinzolamide-hydropropyl-β-cyclodextrin Inclusion Complex: A Potential Therapeutic Ocular Drug-Delivery System
por: Wang, Fazhan, et al.
Publicado: (2018)

Macrophage Foam Cell-Targeting Immunization Attenuates Atherosclerosis
por: Wang, Fazhan, et al.
Publicado: (2019)

Novel Polymeric Hybrid Nanocarrier for Curcumin and Survivin shRNA Co-delivery Augments Tumor Penetration and Promotes Synergistic Tumor Suppression
por: Xu, Bei, et al.
Publicado: (2020)

Pressure-Induced Alterations in PEDF and PEDF-R Expression: Implications for Neuroprotective Signaling in Glaucoma
por: Lee, Sean J, et al.
Publicado: (2015)

PEDF and PEDF-derived peptide 44mer stimulate cardiac triglyceride degradation via ATGL
por: Zhang, Hao, et al.
Publicado: (2015)

Pigment Epithelium‐Derived Factor (PEDF) Improves Ischemic Cardiac Functional Reserve Through Decreasing Hypoxic Cardiomyocyte Contractility Through PEDF Receptor (PEDF‐R)
por: Lu, Peng, et al.
Publicado: (2016)

The Role of PEDF in Reproductive Aging of the Ovary †
por: Nemerovsky, Luba, et al.
Publicado: (2022)

PEDF Inhibits the Activation of NLRP3 Inflammasome in Hypoxia Cardiomyocytes through PEDF Receptor/Phospholipase A2
por: Zhou, Zhongxin, et al.
Publicado: (2016)

PEDF protects cardiomyocytes by promoting FUNDC1-mediated mitophagy via PEDF-R under hypoxic condition
por: Li, Yufeng, et al.
Publicado: (2018)

Ferritin: A Promising Nanoreactor and Nanocarrier for Bionanotechnology
por: Mohanty, Abhinav, et al.
Publicado: (2022)

The Emerging Role of PEDF in Stem Cell Biology
por: Elahy, Mina, et al.
Publicado: (2012)

PEDF – A Noninhibitory Serpin with Neurotrophic Activity
por: Minkevich, N.I., et al.
Publicado: (2010)

PEDF improves cardiac function in rats subjected to myocardial ischemia/reperfusion injury by inhibiting ROS generation via PEDF-R
por: Zhao, Qixiang, et al.
Publicado: (2018)

Pigment Epithelium-Derived Factor (PEDF) Protects Osteoblastic Cell Line from Glucocorticoid-Induced Apoptosis via PEDF-R
por: Yao, Shengcheng, et al.
Publicado: (2016)

Possible role of nanocarriers in drug delivery against cervical cancer
por: Gupta, Swati, et al.
Publicado: (2017)

PEDF and PEDF-derived peptide 44mer protect cardiomyocytes against hypoxia-induced apoptosis and necroptosis via anti-oxidative effect
por: Gao, Xiao, et al.
Publicado: (2014)

Polycaprolactone Nanoparticles as Promising Candidates for Nanocarriers in Novel Nanomedicines
por: Łukasiewicz, Sylwia, et al.
Publicado: (2021)

Codon Preference Optimization Increases Heterologous PEDF Expression
por: Gvritishvili, Anzor G., et al.
Publicado: (2010)

The contrary intracellular and extracellular functions of PEDF in HCC development
por: Li, Cen, et al.
Publicado: (2019)

PEDF Deletion Induces Senescence and Defects in Phagocytosis in the RPE
por: Rebustini, Ivan T., et al.
Publicado: (2022)

Receptors that bind to PEDF and their therapeutic roles in retinal diseases
por: Xu, Manhong, et al.
Publicado: (2023)

Niosome: A Promising Nanocarrier for Natural Drug Delivery through Blood-Brain Barrier
por: Gharbavi, Mahmoud, et al.
Publicado: (2018)

PEDF and its roles in physiological and pathological conditions: implication in diabetic and hypoxia-induced angiogenic diseases
por: He, Xuemin, et al.
Publicado: (2015)

Fr hjahrstagung
por: Schötzau, H J
Publicado: (1994)

PEDF in Diabetic Retinopathy: A Protective Effect of Oxidative Stress
por: Zhu, Xiao-feng, et al.
Publicado: (2012)

Mesenchymal stem cells overexpressing PEDF decrease the angiogenesis of gliomas
por: Wang, Qiaoshu, et al.
Publicado: (2013)

PEDF Is Associated with the Termination of Chondrocyte Phenotype and Catabolism of Cartilage Tissue
por: Klinger, P., et al.
Publicado: (2017)

PEDF inhibits pancreatic tumorigenesis by attenuating the fibro-inflammatory reaction
por: Principe, Daniel R., et al.
Publicado: (2016)

GLUT1 activity contributes to the impairment of PEDF secretion by the RPE
por: Calado, Sofia M., et al.
Publicado: (2016)

Mucoadhesive Nanocarriers as a Promising Strategy to Enhance Intracellular Delivery against Oral Cavity Carcinoma
por: Pandey, Manisha, et al.
Publicado: (2022)

Mannose Treatment: A Promising Novel Strategy to Suppress Inflammation
por: Zhang, Wei, et al.
Publicado: (2021)

Cholesterol-modified Hydroxychloroquine-loaded Nanocarriers in Bleomycin-induced Pulmonary Fibrosis
por: Liu, Li, et al.
Publicado: (2017)

Update on the Use of Nanocarriers and Drug Delivery Systems and Future Directions in Cervical Cancer
por: Himiniuc, Loredana Maria, et al.
Publicado: (2022)

Decay chains of $^{202}Fr$ and $^{204}Fr$ and $\alpha$ decay branches
por: Bingham, C R, et al.
Publicado: (1995)

PEDF regulates lipid metabolism and reduces apoptosis in hypoxic H9c2 cells by inducing autophagy related 5-mediated autophagy via PEDF-R
por: Zhang, Yiqian, et al.
Publicado: (2018)

Enhanced therapeutic effect of PEDF-loaded mesenchymal stem cell-derived small extracellular vesicles against oxygen-induced retinopathy through increased stability and penetrability of PEDF
por: Fan, Ruiyan, et al.
Publicado: (2023)

Predict the Progression of Cervical Intraepithelial Neoplasia by a Novel Marker Folate Combine with FRα, p16 and Ki-67
por: Liu, Tingting, et al.
Publicado: (2022)

PEDF Regulates Vascular Permeability by a γ-Secretase-Mediated Pathway
por: Cai, Jun, et al.
Publicado: (2011)

Pigment Epithelium-Derived Factor (PEDF) as a Regulator of Wound Angiogenesis
por: Michalczyk, Elizabeth R., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ulleihqf1jvh4j3ct4aec5ge5i