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Sobol Sensitivity Analysis: A Tool to Guide the Development and Evaluation of Systems Pharmacology Models

A systems pharmacology model typically integrates pharmacokinetic, biochemical network, and systems biology concepts into a unifying approach. It typically consists of a large number of parameters and reaction species that are interlinked based upon the underlying (patho)physiology and the mechanism...

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Detalles Bibliográficos
Autores principales: Zhang, X‐Y, Trame, MN, Lesko, LJ, Schmidt, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006244/
https://www.ncbi.nlm.nih.gov/pubmed/27548289
http://dx.doi.org/10.1002/psp4.6