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Inversion symmetry of DNA k-mer counts: validity and deviations

BACKGROUND: The generalization of the second Chargaff rule states that counts of any string of nucleotides of length k on a single chromosomal strand equal the counts of its inverse (reverse-complement) k-mer. This Inversion Symmetry (IS) holds for many species, both eukaryotes and prokaryotes, for...

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Detalles Bibliográficos
Autores principales: Shporer, Sagi, Chor, Benny, Rosset, Saharon, Horn, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006273/
https://www.ncbi.nlm.nih.gov/pubmed/27580854
http://dx.doi.org/10.1186/s12864-016-3012-8