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Intermediate filaments enable pathogen docking to trigger type 3 effector translocation
Type 3 secretion systems (T3SSs) of bacterial pathogens translocate bacterial effector proteins that mediate disease into the eukaryotic cytosol. Effectors traverse the plasma membrane through a translocon pore formed by T3SS proteins. In a genome-wide selection, we identified the intermediate filam...
Autores principales: | Russo, Brian C., Stamm, Luisa M., Raaben, Matthijs, Kim, Caleb M., Kahoud, Emily, Robinson, Lindsey R., Bose, Sayantan, Queiroz, Ana L., Herrera, Bobby Brooke, Baxt, Leigh A., Mor-Vaknin, Nirit, Fu, Yang, Molina, Gabriel, Markovitz, David M., Whelan, Sean P., Goldberg, Marcia B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006386/ https://www.ncbi.nlm.nih.gov/pubmed/27572444 http://dx.doi.org/10.1038/nmicrobiol.2016.25 |
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