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Meningitis with polymerase chain reaction for varicella zoster positivity in cerebrospinal flid of a young immunocompetent adult

Meningitis caused by varicella zoster virus (VZV) is quite rare among young immunocompetent adults though immunocompromised patients are often seen to be affected by reactivation of VZV presenting with primary clinical features of dermatomal rashes and neurological sequelae. Here, we report the clin...

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Autores principales: Gupta, Pooja, Ranjan, Rajeev, Agrawal, C. S., Muralikrishnan, K, Dave, Nikhil, Rana, Davinder Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006478/
https://www.ncbi.nlm.nih.gov/pubmed/27695246
http://dx.doi.org/10.4103/0976-3147.185506
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author Gupta, Pooja
Ranjan, Rajeev
Agrawal, C. S.
Muralikrishnan, K
Dave, Nikhil
Rana, Davinder Singh
author_facet Gupta, Pooja
Ranjan, Rajeev
Agrawal, C. S.
Muralikrishnan, K
Dave, Nikhil
Rana, Davinder Singh
author_sort Gupta, Pooja
collection PubMed
description Meningitis caused by varicella zoster virus (VZV) is quite rare among young immunocompetent adults though immunocompromised patients are often seen to be affected by reactivation of VZV presenting with primary clinical features of dermatomal rashes and neurological sequelae. Here, we report the clinical scenario of a young, healthy male who had presented with fever, headache, and onset of dermatomal rashes later than the fever and was eventually diagnosed to be a case of VZV meningitis. We would like to highlight the fact that even young immunocompetent patients though rarely, might contract VZV meningitis and clinicians should have a high index of suspicion and keen eyes to catch the more obvious features of VZV infection on complete physical examination and must not harbor any reservations in ordering polymerase chain reaction for VZV DNA or initiating aggressive antiviral therapy.
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spelling pubmed-50064782016-10-01 Meningitis with polymerase chain reaction for varicella zoster positivity in cerebrospinal flid of a young immunocompetent adult Gupta, Pooja Ranjan, Rajeev Agrawal, C. S. Muralikrishnan, K Dave, Nikhil Rana, Davinder Singh J Neurosci Rural Pract Case Report Meningitis caused by varicella zoster virus (VZV) is quite rare among young immunocompetent adults though immunocompromised patients are often seen to be affected by reactivation of VZV presenting with primary clinical features of dermatomal rashes and neurological sequelae. Here, we report the clinical scenario of a young, healthy male who had presented with fever, headache, and onset of dermatomal rashes later than the fever and was eventually diagnosed to be a case of VZV meningitis. We would like to highlight the fact that even young immunocompetent patients though rarely, might contract VZV meningitis and clinicians should have a high index of suspicion and keen eyes to catch the more obvious features of VZV infection on complete physical examination and must not harbor any reservations in ordering polymerase chain reaction for VZV DNA or initiating aggressive antiviral therapy. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC5006478/ /pubmed/27695246 http://dx.doi.org/10.4103/0976-3147.185506 Text en Copyright: © Journal of Neurosciences in Rural Practice http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Gupta, Pooja
Ranjan, Rajeev
Agrawal, C. S.
Muralikrishnan, K
Dave, Nikhil
Rana, Davinder Singh
Meningitis with polymerase chain reaction for varicella zoster positivity in cerebrospinal flid of a young immunocompetent adult
title Meningitis with polymerase chain reaction for varicella zoster positivity in cerebrospinal flid of a young immunocompetent adult
title_full Meningitis with polymerase chain reaction for varicella zoster positivity in cerebrospinal flid of a young immunocompetent adult
title_fullStr Meningitis with polymerase chain reaction for varicella zoster positivity in cerebrospinal flid of a young immunocompetent adult
title_full_unstemmed Meningitis with polymerase chain reaction for varicella zoster positivity in cerebrospinal flid of a young immunocompetent adult
title_short Meningitis with polymerase chain reaction for varicella zoster positivity in cerebrospinal flid of a young immunocompetent adult
title_sort meningitis with polymerase chain reaction for varicella zoster positivity in cerebrospinal flid of a young immunocompetent adult
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006478/
https://www.ncbi.nlm.nih.gov/pubmed/27695246
http://dx.doi.org/10.4103/0976-3147.185506
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