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Induction of the mesenchymal to epithelial transition by demethylation-activated microRNA-125b is involved in the anti-migration/invasion effects of arsenic trioxide on human chondrosarcoma

BACKGROUND: In addition to treating acute promyelocytic leukemia, arsenic trioxide (ATO) suppresses other solid tumors, including chondrosarcoma. However, the effects of ATO on metastasis in chondrosarcoma cells, and the underlying molecular mechanisms remain unclear. METHODS: The effects of ATO on...

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Detalles Bibliográficos
Autores principales:	Bao, Xing, Ren, Tingting, Huang, Yi, Wang, Shidong, Zhang, Fan, Liu, Kuisheng, Zheng, Bingxin, Guo, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006509/ https://www.ncbi.nlm.nih.gov/pubmed/27576314 http://dx.doi.org/10.1186/s13046-016-0407-y

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